목적: Acellular dermal matrix (ADM) is created from cadaveric skin and widely used material for dorsal augmentation in rhinoplasty. ADM is cross-link structured material, and its collagen matrix has an increased tensile strength and modulus after e-beam irradiation. However, there are rare studies for postoperative long-term histological change of ADM after rhinoplasty. 방법:The patients received revision rhinoplasty with ADM removal procedure was evaluated. The eighteen years old female patient was received operation due to nose deviation arised by displacement of previously inserted ADM. Removed ADM was evaluated grossly about the strength, transition of shape, and the connection with surrounding tissue in the operation room. Then it was cut into several thin pieces in coronal section. Each tissue specimen was stained with Hematoxylin and eosin (H&E) to evaluate the histologic change. 결과:As a gross evaluation, ADM appeared to be well tolerated with the surrounding tissues. It was soft and similar with before insertion status. The thickness of ADM did not change significantly. ADM showed mixture of dense fibrous tissues and skeletal muscles with H&E staining. The main portion of ADM consisted of collagen and elastin fibers, and their arrangement was irregular. Newly formed vascular structure was detected in the periphery of the collagen tissues and granulation tissues. It was usually made up of one layer endothelial cell. It did not reveal definite capsule formation. And fibroblast cell and giant cell were not found. Among inflammatory cells, lymphocyte was infiltrated partly, a sign of chronic mild inflammation. There was no evidence of infection with no foreign body reaction. 결론:Cross-linked human ADM is histologically biocompatible with host tissue ingrowth and cellular infiltration. It can be a suitable implant material with no evidence of infection or graft rejection. Further study is needed to analyze the expression of extracellular matrix proteins at the ADM after operation.