목적: Whether the use of electronic cigarettes (ECs) is associated with upper airway diseases, including chronic rhinosinusitis (CRS) and allergic rhinitis (AR), remains unclear. This study aimed to investigate the association between EC use and the prevalence of CRS and AR. 방법:We analyzed data from the nationwide cross-sectional surveys: the Korea National Health and Nutrition Examination Survey VI (2013–2015), VII (2016–2018), and VIII (2019). Logistic regression analysis was performed to assess the association between EC use and CRS or AR. All statistical analyses were performed using a complex survey design and sampling weights. 결과:A total of 38,413 participants aged ≥19 years were analyzed. The prevalence rates of CRS and AR were 7.3% and 15.4%, respectively. Of all participants, 6.4% were former EC users and 2.5% were current EC users. Logistic regression analysis revealed that former EC users (CRS, adjusted odds ratio [aOR]=1.35, 95% confidence interval [CI]=1.15–1.59, P=0.002; AR, aOR=1.06, 95% CI=0.94–1.20, P=0.002) and current EC users (CRS, aOR=1.08, 95% CI=0.84–1.38, P=0.002; AR, aOR=1.38, 95% CI=1.15– 1.66, P=0.002) showed a significantly increased OR for CRS or AR compared with never EC users. In the subgroup analysis, the “current CC (conventional cigarettes)-current EC” group (CRS, aOR=1.26, 95% CI=0.94–1.68, P<0.001; AR, aOR=1.41, 95% CI=1.14–1.75, P=0.003) and the “current CC-formal EC” group (CRS, aOR=1.41, 95% CI=1.14–1.75, P<0.001; AR, aOR=1.16, 95% CI=0.99–1.35, P=0.003) were found to have a significantly higher OR for CRS or AR than the “current CC-never EC” group. In addition, former CC smokers who currently use ECs (aOR=1.48, 95% CI=1.01–2.17, P=0.017) showed a significantly higher OR for AR than former CC smokers without EC use. 결론:EC use is significantly associated with a high prevalence of CRS and AR in the adult population. These results indicate that the use of ECs may increase the risk of upper airway disease