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접수번호 - 270337 2 |
| COMPARATIVE OUTCOME STUDY BETWEEN SENTINEL NODE BIOPSY AND ELECTIVE NECK
DISSECTION IN CLINICALLY N0 ORAL SQUAMOUS CELL CARCINOMA: SYSTEMATIC
REVIEW AND META-ANALYSIS |
| DEPARTMENT OF OTORHINOLARYNGOLOGY-HEAE AND NECK SURGERY, INJE UNIVERSITY SCHOOL OF MEDICINE, ILSAN PAIK HOSPITAL¹, DEPARTMENT OF OTORHINOLARYNGOLOGY-HEAD AND NECK SURGERY, SUNGKYUNKWAN UNIVERSITY SCHOOL OF MEDICINE, SAMSUNG MEDICAL CENTER², STATISTICS AND DATA CENTER, RESEARCH INSTITUTE FOR FUTURE MEDICINE, SAMSUNG MEDICAL CENTER³ |
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KEUN-WOO JUNG¹, NAYEON CHOI², MIN-JI KIM³, MAN KI CHIUNG², AND JAE-KEUN CHO¹ |
목적: To provide a considerable evidence on the comparative effectiveness of
two surgical treatment methods, sentinel lymph node biopsy (SNB) and
elective neck dissection (END), in patients with early oral squamous
cell carcinoma and clinical node negative, in terms of overall survival
(OS), disease-free survival (DFS), and quality of life (QOL). 방법:A systematic review was performed by including studies published up to
June 2021. Meta-analysis was conducted to compare treatment outcome
including OS and DFS between SNB and END group. Other outcomes 결과:Two randomized studies and 9 non randomized studies were retrieved. The
pooled risk ratio showed no differences in treatment outcome between SNB
and END(80.2% vs 78.8% vs 80.2 in DFS; pooled RR 1.09; 95% CI 0.76-1.54,
81.6% vs 81.1 in OS; pooled RR 1.04; 95% CI 0.63-1.48). SNB appears to
be associated with a lower rate of postoperative complications including
shoulder dysfunction than END. 결론:This study demonstrated the oncologic equivalance of the SNB and END
approach with lower morbidity.
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